Difference between pain relief tablets?

I have regular 500mg Paracetamol tablets and Panadeine tablets that contain 500mg paracetamol and 8mg codeine phosphate. Is that 8 mg of codeine REALLY makes any difference? Is it going to be a significant difference or is it just a trick from pharmaceutical companies to make people feel better phyhologicly?

Chosen Answer:

Codeine can make a difference although 8 mg is a low dose. In some patients codeine works as well as taking a pez due to the fact that they lack the cytochrome required to metabolize codeine. Codeine is metabolized to morphine. Analgesic properties are attributed to the morphine

4 Responses to “Difference between pain relief tablets?”

  1. W W D says:

    A reasonable codeine dose would be 30-60 mg, but that would be a toxic dose of paracetamol in the combination pill. The Panadeine is the end-result of governmental overcaution, I suspect. Here in the US, any amount of codeine in a tablet requires a controlled prescription.

  2. corksoaker197 says:

    Codeine can make a difference although 8 mg is a low dose. In some patients codeine works as well as taking a pez due to the fact that they lack the cytochrome required to metabolize codeine. Codeine is metabolized to morphine. Analgesic properties are attributed to the morphine

  3. TomB says:

    8mg of Codeine is a VERY low dose. I don’t know why they would even bother. 30-60mg is the normal dose.